Cytotoxic C-benzylated dihydrochalcones from Uvaria acuminata.
نویسندگان
چکیده
Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), isouvaretin (5), diuvaretin (6), and uvangoletin (7). The structural elucidation of compounds 1 and 2 in spectroscopic studies is described. C-Benzylated dihydrochalcones, especially 1, 2, 4, and 6, showed considerable cytotoxicity toward human promyelocytic leukemia HL-60 cells.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 52 1 شماره
صفحات -
تاریخ انتشار 2004